Role of Viagra Sildenafil In Pulmonary Hypertension

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Pulmonary hypertension is supposed to rise in pressure of pulmonary artries. Some ailments can narrow the blood vessels in the lungs, which leads to high blood pressure in the lungs when blood pressure in the rest of the body is normal. It could possibly be a result of lung diseases or heart ailments. Pulmonary hypertension is a highly fatal disorder since the strain of pumping blood through narrowed vessels frequently leads to collapse of the heart muscle. When the heart muscle fails, the lungs cannot supply enough oxygen to satisfy the body’s wants.

There are various treaments out there for pulmonary hypertension. Aims of treament are:

Dilate pancreatic vessels

Decrease preload on heart

Increase oxygen source to lungs

Prevention and treatment of respiratory disease

Increase cardiac output

Heal cause of secondary hypertension.

Any treatment which dilates pulmonary vessels can decease pulmonary hypertension. Remedies for this disorder widen the damaged blood vessels in the gut and make it easier for the heart to pump blood through the lungs cialis.

One such medication (epoprostenol) is effective only if given intravenously via a little plastic tube that has to stay in the vein indefinitely. Another treatment involves constant inhalation of a gas (nitric oxide) that also widens blood vessels in the lungs. A newer strategy has been an inhaled mist form of epoprostenol known as iloprost. Since each mist treatment lasts only about 60 minutes, up to 12 treatments each day are required. Each of these treatments has its drawbacks and side effects. You cant take these orally, and also have shorter duration of activity. Lately, researchers discovered that a medication Viagra (sildenafil citrate) the erectile-dysfunction drug employed by more than 26 million men worldwide,can enhance and prolong the activities of both iloprost and nitric oxide.

Viagra’s Active Ingredient Treats Pulmonary Hypertension
New drug Revatio, which includes sildenafil citrate, the same active ingredient found at the erectile-dysfunction drug Viagra, has been accepted by the Food and Drug Administration (FDA) for treating pulmonary hypertension. Revatio is round and white; Viagra is a grim diamond.Will the medication work long-term? “Only time will tell,” says Norman Edelman, medical director of the American Lung Association. “Anything which lowers blood pressure in the lungs and can do it will probably prolong life.”

Good thing about this medication”it could be given orally, instead of intravenously or within an injection.” The only other drug which may be given orally, Bosentan, can damage the liver. Studies are underway to find out whether Revatio could be awarded with Bosentan along with other drugs to yield a much larger benefit.

Negative erections have been noted but very infrequent instances.

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